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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
Describedennisitarities who have used Cialis before have shown some improvement in blood pressure when stopped. However, tadalafil has been associated with an increased risk of cardiovascular events such as a stroke or heart attack.

C.

Cialis (tadalafil) can interact with certain foods and beverages, such as grapefruit and grapefruit juice, and may alter its effectiveness or enhance the risk of side effects. Here are the key drug-food interactions:

  1. : Though not a direct interaction, combining Cialis with high alcohol consumption might worsen side effects like headaches or increase blood pressure in sensitive individuals.
  2. : While showing improvement while taking Cialis,zens of other interactions have been reported, mostly in those with a high-fat meal.

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Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Applies to Cialis – Health Care provider (HCP) to: My age 40+ 55. I buy viagra online cheap buy cialis

HCPs must be prescribed Cialis by a health care provider who can assess your medical condition and ensure that it is safe for you to take. This includes a health care provider who can prescribe Cialis and monitor you closely for side effects.

HCPs are responsible for determining if Cialis is right for you. If it is, your HCP will assess your medical condition and provide you with a safe Cialis dosage. This may include providing you with a doctor’s prescription, if applicable, before you have sex.

HCPs are responsible for determining whether Cialis is safe and appropriate for you to take. This includes your health care provider.

Applies to Cialis - Health Care provider (HCP) to health care provider (HCP) with insurance (if available).

HCPs are responsible for providing the HCP with access to information and supplies during potential interactions with other HCPs.

HCPs are responsible for providing the HCP with medical advice during potential interactions with other HCPs.

HCPs are responsible for providing the HCP with access to information and supplies during potential interactions with other health care providers.

HCPs are responsible for providing the HCP with follow-up care when needed.

Applies to Health Care provider (HCP) to health care provider with insurance (if available).
  • Medicines and supplements that can interact with Cialis
  • Herbal supplements that can interact with Cialis
  • St. John's wort
  • Fungal infections that can interact with Cialis
  • Other medicines (e.g.

This article is provided by, a collaboration between Harvard Health Publishing and.

Cialis and Viagra are both drugs that work to treat erectile dysfunction. They are both medications that can treat other conditions.

These drugs can help with symptoms of impotence or erectile dysfunction but they do so only on the advice of a healthcare professional.

How Cialis and Viagra Work

Cialis (Tadalafil) and Viagra (Vardenafil) work to treat both erectile dysfunction and benign prostatic hyperplasia. They help treat erectile dysfunction, which is the inability to get or keep an erection when you’re sexually stimulated.

The drugs work by increasing blood flow to the penis, helping to achieve an erection.

Cialis and Viagra do not work in the same way or as an effective treatment for erectile dysfunction. If you have erectile dysfunction, talk to your doctor about whether you can get treatment for it.

What is Viagra?

Viagra (sildenafil) and Cialis (tadalafil) are two drugs that work to treat erectile dysfunction.

These drugs work by increasing blood flow to the penis, helping to achieve an erection. However, they do so only on the advice of a healthcare professional.

If you have erectile dysfunction and you have questions about whether you can get treatment for erectile dysfunction, talk to your doctor.